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PNLIP Protein (AA 245-465) (His tag)

PNLIP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505074
  • Target See all PNLIP Proteins
    PNLIP (Pancreatic Lipase (PNLIP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 245-465
    Origin
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PNLIP protein is labelled with His tag.
    Sequence
    Pro 245-Cys 465
    Characteristics
    A DNA sequence encoding the Human PL protein (P16233) (Pro245-Cys465) was expressed with a N-His .
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product PNLIP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    PNLIP (Pancreatic Lipase (PNLIP))
    Alternative Name
    Pancreatic lipase (PNLIP Products)
    Synonyms
    PL Protein, PNLIPD Protein, PTL Protein, LIPASE Protein, PANLI Protein, 1810007A24Rik Protein, PNLIP Protein, PNLIPRP2 Protein, pancreatic lipase Protein, PNLIP Protein, Pnlip Protein, pnlip Protein
    Background

    Abbreviation: Pancreatic lipase,PL

    Target Synonym: Pancreatic triacylglycerol lipase,PL,PTL,Pancreatic lipase,PNLIP

    Background: PNLIP is an enzyme which belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the lipase to break apart the fat more effectively. The resulting monomers (2 free fatty acids and one 2-monoacylglycerol) are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal.

    Molecular Weight

    Calculated MW: 24.2 kDa

    Observed MW: 30 kDa

    UniProt
    P16233
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