CFHR1 Protein (AA 205-329) (His tag)

Catalog No. ABIN7505070

Product Details

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Protein Type: Recombinant

Protein Characteristics: AA 205-329

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CFHR1 protein is labelled with His tag.

Sequence: Thr205-Lys329

Characteristics: A DNA sequence encoding the Human CFHR1 protein (Q03591) (Thr205-Lys329) was expressed with a N-His .

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: CFHR1 (CFHR1 Products)

Synonyms: AI194696 Protein, CFHRB Protein, Cfhl1 Protein, CFHL Protein, CFHL1 Protein, CFHL1P Protein, CFHR1P Protein, FHR1 Protein, H36-1 Protein, H36-2 Protein, HFL1 Protein, HFL2 Protein, complement factor H-related 1 Protein, complement factor H-related protein 1 Protein, complement factor H related 1 Protein, Cfhr1 Protein, LOC735590 Protein, LOC746429 Protein, CFHR1 Protein

Background:

Abbreviation: CFHR1

Target Synonym: Complement Factor H-Related Protein 1,FHR-1,H Factor-Like Protein 1,H-Factor-Like 1,H36,CFHR1,CFHL,CFHL1,CFHL1P,CFHR1P,FHR1,HFL1,HFL2

Background: Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS.

Molecular Weight:

Calculated MW: 13.64 kDa

Observed MW: 15 kDa

UniProt: Q03591