PIGR Protein (AA 19-561) (His tag)
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- Target See all PIGR Proteins
- PIGR (Polymeric Immunoglobulin Receptor (PIGR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-561
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PIGR protein is labelled with His tag.
- Sequence
- Lys 19-Ala 561
- Characteristics
- A DNA sequence encoding the Human PIGR/SC protein (P01833) (Lys 19-Ala 561) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PIGR Protein
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Polymeric Immunoglobulin Receptor (PIGR) (AA 21-130) protein (GST tag)
PIGR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Polymeric Immunoglobulin Receptor (PIGR) (Active) protein (His tag)PIGR Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PIGR (Polymeric Immunoglobulin Receptor (PIGR))
- Alternative Name
- PIGR (PIGR Products)
- Synonyms
- DKFZp469G1013 Protein, RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein
- Background
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Abbreviation: PIGR;SC
Target Synonym: Polymeric Immunoglobulin Receptor;PIgR;Poly-Ig Receptor;PIGR
Background: Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
- Molecular Weight
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Calculated MW: 59.62 kDa
Observed MW: 59 kDa
- UniProt
- P01833
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