GAL Protein (AA 33-123) (GST tag)

Catalog No. ABIN7505061

Product Details

Target: GAL (Galanin Prepropeptide (GAL))

Protein Type: Recombinant

Protein Characteristics: AA 33-123

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GAL protein is labelled with GST tag.

Sequence: Gly 33-Ser 123

Characteristics: A DNA sequence encoding the Human GAL protein (P22466) (Gly 33-Ser 123) was expressed with a N-GST tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: GAL (Galanin Prepropeptide (GAL))

Alternative Name: GAL (GAL Products)

Synonyms: xgal Protein, galanin Protein, Galn Protein, GALN Protein, GAL-GMAP Protein, GLNN Protein, GMAP Protein, galanin prepropeptide, gene 2 Protein, galanin Protein, galanin and GMAP prepropeptide Protein, gal.2 Protein, Gal Protein, GAL Protein

Background:

Abbreviation: GAL

Target Synonym: GAL-GMAP,GALN,GLNN,GMAP

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD180, also known as RP105, is a B-cell surface molecule belonging to the family of pathogen receptors, Toll-like receptors (TLR). CD180 has an extracellular leucine-rich repeats and a short cytoplasmic tail. CD180 / RP105 interact with an extracellular molecule named MD1 and then together form the cell surface receptor complex RP105 / MD1 which induces B-cell activation in humans and mice, leading to proliferation and up-regulation of a costimulatory molecule, B7.2 / CD86. CD180 / RP105 also has a role in LPS response because B cells lacking RP105 show hyporesponsiveness to LPS.

Molecular Weight:

Calculated MW: 34.9 kDa

Observed MW: 35 kDa

UniProt: P22466

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Feeding Behaviour