PNOC Protein (AA 20-176) (His tag)

Catalog No. ABIN7505059

Product Details

Target: PNOC (Prepronociceptin (PNOC))

Protein Type: Recombinant

Protein Characteristics: AA 20-176

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PNOC protein is labelled with His tag.

Sequence: Ser 20-Val 176

Characteristics: A DNA sequence encoding the Human OFQ/N protein (Q13519) (Ser 20-Val 176) was expressed with a N-His tag.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: PNOC (Prepronociceptin (PNOC))

Alternative Name: OFQ (PNOC Products)

Synonyms: N23K Protein, Npnc1 Protein, PPNOC Protein, N/OFQ Protein, OFQ/N Protein, PNOC Protein, OFQ Protein, prepronociceptin Protein, PNOC Protein, Pnoc Protein

Background:

Abbreviation: PNOC,OFQ

Target Synonym: PNOC,N/OFQ,NOP,OFQ,PPNOC,ppN/OFQ,Prepronociceptin

Background: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin.

Molecular Weight:

Calculated MW: 17.16 kDa

Observed MW: 23 kDa

UniProt: Q13519