Lactate Dehydrogenase A Protein (LDHA) (AA 2-332) (His tag)
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- Target See all Lactate Dehydrogenase A (LDHA) Proteins
- Lactate Dehydrogenase A (LDHA)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-332
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Lactate Dehydrogenase A protein is labelled with His tag.
- Sequence
- Ala 2-Phe 332
- Characteristics
- A DNA sequence encoding the Human LDHA protein (P00338) (Ala 2-Phe 332) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product LDHA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Lactate Dehydrogenase A (LDHA)
- Alternative Name
- LDHA (LDHA Products)
- Synonyms
- GSD11 Protein, LDH1 Protein, LDHM Protein, LDH-M Protein, ldh-h Protein, ldha Protein, ldha-B Protein, ldhbb Protein, trg-5 Protein, Ldh1 Protein, Ldhm Protein, l7R2 Protein, gsd11 Protein, ldh-m Protein, ldh1 Protein, ldhm Protein, pig19 Protein, ldha1 Protein, ldhab Protein, LDH-A Protein, LDHC Protein, lactate dehydrogenase A Protein, lactate dehydrogenase B L homeolog Protein, lactate dehydrogenase A4 Protein, lactate dehydrogenase A L homeolog Protein, L-lactate dehydrogenase A chain Protein, LDHA Protein, ldhb.L Protein, Ldha Protein, ldha Protein, ldha.L Protein, LOC100713875 Protein
- Background
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Abbreviation: LDHA
Target Synonym: L-Lactate Dehydrogenase A Chain,LDH-A,Cell Proliferation-Inducing Gene 19 Protein,LDH Muscle Subunit,LDH-M,Renal Carcinoma Antigen NY-REN-59,LDHA
Background: L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
- Molecular Weight
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Calculated MW: 36.3 kDa
Observed MW: 39 kDa
- UniProt
- P00338
- Pathways
- Warburg Effect
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