UCP1 Protein (AA 1-307) (His tag)
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- Target See all UCP1 Proteins
- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-307
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UCP1 protein is labelled with His tag.
- Sequence
- Met 1-Thr 307
- Characteristics
- A DNA sequence encoding the Human UCP1 protein (P25874) (Met 1-Thr 307) was expressed with a N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UCP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
- Alternative Name
- UCP1 (UCP1 Products)
- Synonyms
- ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 Protein, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 Protein, ATPUMP1 Protein, ATUCP1 Protein, UCP Protein, UCP1 Protein, UNCOUPLING PROTEIN 1 Protein, plant uncoupling mitochondrial protein 1 Protein, ucp Protein, slc25a7 Protein, SLC25A7 Protein, AI385626 Protein, Slc25a7 Protein, Ucp Protein, Ucpa Protein, Uncp Protein, plant uncoupling mitochondrial protein 1 Protein, uncoupling protein 1 Protein, uncoupling protein 1 L homeolog Protein, uncoupling protein 1 (mitochondrial, proton carrier) Protein, PUMP1 Protein, UCP1 Protein, ucp1.L Protein, ucp1 Protein, Ucp1 Protein
- Background
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Abbreviation: UCP1
Target Synonym: UCP1,SLC25A7,UCP
Background: Mitochondrial brown fat uncoupling protein 1 (UCP1, also Thermogenin and UCP) is a 33 kDa member of the mitochondrial carrier family of proteins. Human UCP1 are both 307 amino acids (aa) in length and contain three solcar repetitive regions and six transmembrane segments. UCP1 is found in brown adipose tissue, where it becomes activated by fatty acids and inhibited by nucleotides. It functions as a mitochondrial transporter that creates a proton leak across the inner mitochondrial membrane, uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
- Molecular Weight
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Calculated MW: 33.66 kDa
Observed MW: 31 kDa
- UniProt
- P25874
- Pathways
- Proton Transport, Brown Fat Cell Differentiation
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