Cathelicidin Protein (AA 134-170) (GST tag)
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- Target See all Cathelicidin (CAMP) Proteins
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 134-170
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Cathelicidin protein is labelled with GST tag.
- Sequence
- Leu 134-Ser 170
- Characteristics
- A DNA sequence encoding the Human LL-37 protein (P49913) (Leu134-Ser170) was expressed with a GST.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CAMP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- Alternative Name
- LL-37 (CAMP Products)
- Synonyms
- CAP-18 Protein, CAP18 Protein, CRAMP Protein, FALL-39 Protein, FALL39 Protein, LL37 Protein, CATH-2 Protein, Cnlp Protein, Cramp Protein, MCLP Protein, CATH-B1 Protein, CATHB1 Protein, CATHL2 Protein, CATHL7 Protein, CAP11 Protein, cathelicidin antimicrobial peptide Protein, CAMP Protein, LOC100136187 Protein, LOC100136439 Protein, Camp Protein
- Background
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Abbreviation: LL-37
Target Synonym: Cathelicidin antimicrobial peptide,CAMP_HUMAN,CAMP,18 kDa cationic antimicrobial protein,CAP-18,hCAP-18,FALL39,HSD26
Background: Antimicrobial protein that is an integral component of the innate immune system. Binds to bacterial lipopolysaccharides (LPS). Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2. Postsecretory processing generates multiple cathelicidin antimicrobial peptides with various lengths which act as a topical antimicrobial defense in sweat on skin. The unprocessed precursor form, cathelicidin antimicrobial peptide, inhibits the growth of Gram-negative E.coli and E.aerogenes with efficiencies comparable to that of the mature peptide LL-37 (in vitro).
- Molecular Weight
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Calculated MW: 28.96 kDa
Observed MW: 32 kDa
- UniProt
- P49913
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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