UCHL1 Protein (AA 1-220) (GST tag)
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- Target See all UCHL1 Proteins
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-220
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UCHL1 protein is labelled with GST tag.
- Sequence
- Met1-Cys220
- Characteristics
- A DNA sequence encoding the Human UCHL1 protein (P09936) (Met1-Cys220) was expressed with a GST.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UCHL1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- Alternative Name
- UCHL1 (UCHL1 Products)
- Synonyms
- PARK5 Protein, PGP 9.5 Protein, PGP9.5 Protein, PGP95 Protein, Uch-L1 Protein, UCH-L1 Protein, UCHL1 Protein, cb358 Protein, wu:fc55h08 Protein, park5 Protein, pgp9.5 Protein, uch-l1 Protein, MGC132191 Protein, uchl1 Protein, AW822034 Protein, C88048 Protein, R75593 Protein, UCHL-1 Protein, gad Protein, ubiquitin C-terminal hydrolase L1 Protein, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) Protein, ubiquitin C-terminal hydrolase L1 L homeolog Protein, ubiquitin carboxyl-terminal esterase L1 Protein, ubiquitin carboxy-terminal hydrolase L1 Protein, UCHL1 Protein, uchl1 Protein, uchl1.L Protein, LOC100304750 Protein, Uchl1 Protein
- Background
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Abbreviation: UCHL1
Target Synonym: Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1,UCH-L1,Neuron Cytoplasmic Protein 9.5,PGP 9.5,PGP9.5,Ubiquitin Thioesterase L1,UCHL1,HEL-117,NDGOA,PARK5,Uch-L1
Background: Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.
- Molecular Weight
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Calculated MW: 49.09 kDa
Observed MW: 30 kDa
- UniProt
- P09936
- Pathways
- Feeding Behaviour
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