Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)
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- Target See all Ataxin 2 (ATXN2) Proteins
- Ataxin 2 (ATXN2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 460-600
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Ataxin 2 protein is labelled with GST tag.
- Sequence
- Leu 460-Ser 600
- Characteristics
- A DNA sequence encoding the Human ATXN2 protein (Q99700) (Leu460-Ser600) was expressed with a N-GST tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ATXN2 Protein
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Ataxin 2 (ATXN2) (AA 1-1313) protein (Strep Tag)
ATXN2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ataxin 2 (ATXN2) (AA 1-165) protein (His tag)ATXN2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Ataxin 2 (ATXN2) (AA 1214-1313) protein (GST tag)ATXN2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Ataxin 2 (ATXN2)
- Alternative Name
- ATXN2 (ATXN2 Products)
- Synonyms
- ASL13 Protein, ATX2 Protein, SCA2 Protein, TNRC13 Protein, 9630045M23Rik Protein, AW544490 Protein, Sca2 Protein, ATXN2 Protein, MGC115230 Protein, ataxin 2 Protein, ataxin 2 L homeolog Protein, ATXN2 Protein, Atxn2 Protein, atxn2.L Protein
- Background
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Abbreviation: ATXN2
Target Synonym: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2,SCA2,TNRC13
Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
- Molecular Weight
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Calculated MW: 40.4 kDa
Observed MW: 42 kDa
- UniProt
- Q99700
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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