FSHB Protein (AA 1-129) (His tag)

Catalog No. ABIN7505033

Product Details

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Protein Type: Recombinant

Protein Characteristics: AA 1-129

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This FSHB protein is labelled with His tag.

Sequence: Met1-Glu129

Characteristics: A DNA sequence encoding the Human FSH-b protein (P01225) (Met1-Glu129) was expressed with a C-His.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))

Alternative Name: FSH-b (FSHB Products)

Synonyms: gthI Protein, fsh-beta Protein, LOC100136594 Protein, FSHB Protein, LOC100218526 Protein, FSH Protein, Fshbeta Protein, FSH-beta Protein, follicle stimulating hormone, beta polypeptide Protein, follicle stimulating hormone beta subunit L homeolog Protein, follcle-stimulating hormone beta subunit Protein, follicle stimulating hormone beta subunit Protein, follicle stimulating hormone beta Protein, follitropin subunit beta Protein, fshb Protein, fshb.L Protein, LOC100136594 Protein, FSHB Protein, Fshb Protein

Background:

Abbreviation: FSH-b

Target Synonym: Follitropin Subunit Beta,Follicle-Stimulating Hormone Beta Subunit,FSH-B,FSH-Beta,Follitropin Beta Chain,FSHB

Background: Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD).

Molecular Weight:

Calculated MW: 14.08 kDa

Observed MW: 28 kDa

UniProt: P01225

Pathways: Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process