CCL14 Protein (AA 20-93)

Catalog No. ABIN7504986

Product Details

Target: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Protein Type: Recombinant

Protein Characteristics: AA 20-93

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: Thr20-Asn93

Characteristics: A DNA sequence encoding the Human CCL14 Protein(Q16627-1)(Thr20-Asn93)was expressed with a polyhistidine tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

Alternative Name: CCL14 (CCL14 Products)

Synonyms: CCL14 Protein, CC-1 Protein, CC-3 Protein, CKB1 Protein, HCC-1 Protein, HCC-1(1-74) Protein, HCC-1/HCC-3 Protein, HCC-3 Protein, MCIF Protein, NCC-2 Protein, NCC2 Protein, SCYA14 Protein, SCYL2 Protein, SY14 Protein, C-C motif chemokine ligand 14 Protein, C-C motif chemokine 14 Protein, chemokine (C-C motif) ligand 14 Protein, CCL14 Protein, Ccl14 Protein, LOC480603 Protein, LOC101115044 Protein

Background:

Abbreviation: CCL14

Target Synonym: C-C motif chemokine 14,CC-1,CC-3,HCC-1,HCC-1(1-74),HCC-3,NCC-2,Small-inducible cytokine A14,NCC2,SCYA14

Background: Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induces intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.

Molecular Weight:

Calculated MW: 8.7 kDa

Observed MW: 12 kDa

UniProt: Q16627