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LTA Protein (AA 35-205)

LTA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7504984
  • Target See all LTA Proteins
    LTA (Lymphotoxin-alpha (LTA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 35-205
    Origin
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 22
    • 6
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    Leu35-Leu205
    Characteristics
    A DNA sequence encoding the Human TNF β/LTA Protein(P01374)(Leu35-Leu205)was expressed with a polyhistidine tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
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    Discover our top product LTA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    LTA (Lymphotoxin-alpha (LTA))
    Alternative Name
    TNF beta (LTA Products)
    Synonyms
    LT Protein, TNFB Protein, TNFSF1 Protein, LT-[a] Protein, LT-alpha Protein, LT[a] Protein, LTalpha Protein, Ltx Protein, TNF-beta Protein, Tnfb Protein, Tnfsf1b Protein, hlb382 Protein, lymphotoxin alpha Protein, lymphotoxin A Protein, LTA Protein, Lta Protein
    Target Type
    Chemical
    Background

    Abbreviation: TNF β,LTA

    Target Synonym: Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,LTA,TNFB,TNFSF1

    Background: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.

    Molecular Weight

    Calculated MW: 18.7 kDa

    Observed MW: 19 kDa

    UniProt
    P01374
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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