LTA Protein (AA 35-205)
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- Target See all LTA Proteins
- LTA (Lymphotoxin-alpha (LTA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 35-205
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- Leu35-Leu205
- Characteristics
- A DNA sequence encoding the Human TNF β/LTA Protein(P01374)(Leu35-Leu205)was expressed with a polyhistidine tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product LTA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- LTA (Lymphotoxin-alpha (LTA))
- Alternative Name
- TNF beta (LTA Products)
- Synonyms
- LT Protein, TNFB Protein, TNFSF1 Protein, LT-[a] Protein, LT-alpha Protein, LT[a] Protein, LTalpha Protein, Ltx Protein, TNF-beta Protein, Tnfb Protein, Tnfsf1b Protein, hlb382 Protein, lymphotoxin alpha Protein, lymphotoxin A Protein, LTA Protein, Lta Protein
- Target Type
- Chemical
- Background
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Abbreviation: TNF β,LTA
Target Synonym: Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,LTA,TNFB,TNFSF1
Background: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
- Molecular Weight
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Calculated MW: 18.7 kDa
Observed MW: 19 kDa
- UniProt
- P01374
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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