IL-15 Protein (AA 49-162)

Catalog No. ABIN7504981

Product Details

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Protein Type: Recombinant

Protein Characteristics: AA 49-162

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: Asn49-Ser162

Characteristics: A DNA sequence encoding the Human IL15 Protein(P40933)(Asn49-Ser162)was expressed with a polyhistidine tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Alternative Name: IL15 (IL15 Products)

Synonyms: IL15 Protein, AI503618 Protein, IL-15 Protein, interleukin 15 Protein, IL15 Protein, Il15 Protein

Background:

Abbreviation: IL-15

Target Synonym: Interleukin-15,IL-15,

Background: Cytokine that stimulates the proliferation of T-lymphocytes (PubMed:8178155). Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (PubMed:8178155). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (PubMed:15123770).

Molecular Weight:

Calculated MW: 15.1 kDa

Observed MW: 15 kDa

UniProt: P40933

Pathways: JAK-STAT Signaling, Glycosaminoglycan Metabolic Process