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IL-4 Protein (AA 25-153)

IL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7504977
  • Target See all IL-4 (IL4) Proteins
    IL-4 (IL4) (Interleukin 4 (IL4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-153
    Origin
    • 29
    • 13
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 37
    • 20
    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    His25-Ser153
    Characteristics
    A DNA sequence encoding the Human IL4 protein (P05112) (His25-Ser153) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IL4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    IL-4 (IL4) (Interleukin 4 (IL4))
    Alternative Name
    IL-4 (IL4 Products)
    Synonyms
    IL4 Protein, IL-4 Protein, BCGF-1 Protein, BCGF1 Protein, BSF-1 Protein, BSF1 Protein, Il-4 Protein, Il4e12 Protein, IL2 Protein, interleukin 4 Protein, IL4 Protein, Il4 Protein
    Background

    Abbreviation: IL-4

    Target Synonym: Interleukin-4,IL4,B-cell stimulatory factor 1,BSF-1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra

    Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

    Molecular Weight

    Calculated MW: 15 kDa

    Observed MW: 16 kDa

    UniProt
    P05112
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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