Periostin Protein (POSTN) (AA 21-365) (His tag)

Catalog No. ABIN7504938

Product Details

Target: Periostin (POSTN)

Protein Type: Recombinant

Protein Characteristics: AA 21-365

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Periostin protein is labelled with His tag.

Sequence: Ala21-Leu365

Characteristics: A DNA sequence encoding the Human POSTN (Q15063-1) (Ala21-Leu365) was expressed with a polyhistidine tag at the N-terminus.

Purity: > 85 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris,1 mM EDTA, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Preservative: Other preservative

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Periostin (POSTN)

Alternative Name: POSTN (POSTN Products)

Synonyms: fa99h07 Protein, pn Protein, postn Protein, wu:fa99h07 Protein, wu:fc70f09 Protein, zgc:153873 Protein, LOC100008945 Protein, osf-2 Protein, pdlpostn Protein, periostin Protein, OSF-2 Protein, OSF2 Protein, PDLPOSTN Protein, PN Protein, RP11-412K4.1 Protein, A630052E07Rik Protein, AI747096 Protein, Osf2 Protein, PLF Protein, peri Protein, Plf Protein, periostin Protein, periostin, osteoblast specific factor b Protein, periostin, osteoblast specific factor Protein, POSTN Protein, postnb Protein, postn Protein, Postn Protein

Background:

Abbreviation: POSTN

Target Synonym: Fasciclin-I like,MGC119510,MGC119511,OSF 2,OSF-2,OSF2,Osteoblast specific factor 2 (fasciclin I like),Osteoblast specific factor 2,Osteoblast specific factor,Osteoblast-specific factor 2,PDLPOSTN,Periodontal ligament specific periostin,Periostin,Periostin isoform thy2,Periostin isoform thy4,Periostin isoform thy6,Periostin isoform thy8,Periostin osteoblast specific factor,PN,POSTN,POSTN,RP11 412K4.1

Background: Periostin (POSTN,PN),originally named as osteoblast-specific factor 2 (OSF-2),is a 90- kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.

Molecular Weight:

Calculated MW: 38 kDa

Observed MW: 40.3 kDa

UniProt: Q15063-1