EpCAM Protein (AA 24-265) (His tag)

Catalog No. ABIN7504930

Product Details

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Protein Type: Recombinant

Protein Characteristics: AA 24-265

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EpCAM protein is labelled with His tag.

Sequence: Glu24-Lys265

Characteristics: A DNA sequence encoding the Human EpCAM (P16422-1) (Glu24-Lys265) was expressed with a polyhistidine tag at the N-terminus.

Purity: > 85 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Alternative Name: EpCAM (EPCAM Products)

Synonyms: DIAR5 Protein, EGP-2 Protein, EGP314 Protein, EGP40 Protein, ESA Protein, HNPCC8 Protein, KS1/4 Protein, KSA Protein, M4S1 Protein, MIC18 Protein, MK-1 Protein, TACSTD1 Protein, TROP1 Protein, ECS-1 Protein, ECS1 Protein, ESA1 Protein, M17S1 Protein, EGP Protein, Ep-CAM Protein, sb:cb6 Protein, tacstd Protein, wu:fj17g02 Protein, zgc:110304 Protein, zgc:77119 Protein, tacstd1 Protein, MGC80540 Protein, EPCAM Protein, egp Protein, ksa Protein, m4s1 Protein, mk-1 Protein, cd326 Protein, egp40 Protein, mic18 Protein, trop1 Protein, ep-cam Protein, hegp-2 Protein, co17-1a Protein, ga733-2 Protein, CD326 Protein, Egp314 Protein, EpCAM1 Protein, GA733-2 Protein, Ly74 Protein, Tacsd1 Protein, Tacstd1 Protein, gp40 Protein, epithelial cell adhesion molecule Protein, flotillin 2 Protein, epithelial cell adhesion molecule S homeolog Protein, EPCAM Protein, FLOT2 Protein, epcam Protein, epcam.S Protein, Epcam Protein

Background:

Abbreviation: EpCAM

Target Synonym: Epithelial cell adhesion molecule,Ep-CAM,Adenocarcinoma-associated antigen,Cell surface glycoprotein Trop-1,Epithelial cell surface antigen,Epithelial glycoprotein,EGP,Epithelial glycoprotein 314,EGP314,hEGP314,KS 1/4 antigen.KSA,Major gastrointestinal tumor-associated protein GA733-2,Tumor-associated calcium signal transducer 1,CD326,EPCAM,GA733-2,M1S2,M4S1,MIC18,TACSTD1,TROP1

Background: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Molecular Weight:

Calculated MW: 27.42 kDa

Observed MW: 29.72 kDa

UniProt: P16422-1