ABL1 Protein (AA 1-264) (His tag)
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- Target See all ABL1 Proteins
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-264
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Origin
- Cynomolgus
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ABL1 protein is labelled with His tag.
- Sequence
- Met 1-Phe 264
- Characteristics
- A DNA sequence encoding theCynomolgus macaques ABL1 protein (A0A2K5X6F2) (Met 1-Phe 264) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ABL1 Protein
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C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 931-1030) protein (GST tag)
ABL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (Active) protein (GST tag)ABL1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 75 % as determined by reducing SDS-PAGE. Active
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 4-194), (partial) protein (GST tag)ABL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 4-194), (partial) protein (GST tag)ABL1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- Alternative Name
- ABL1 (ABL1 Products)
- Synonyms
- ABL Protein, JTK7 Protein, bcr/abl Protein, c-ABL Protein, p150 Protein, v-abl Protein, AI325092 Protein, Abl Protein, E430008G22Rik Protein, c-Abl Protein, ABL proto-oncogene 1, non-receptor tyrosine kinase Protein, c-abl oncogene 1, non-receptor tyrosine kinase Protein, Tyrosine-protein kinase abl-1 Protein, ABL1 Protein, Abl1 Protein, abl-1 Protein, abl1 Protein
- Background
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Abbreviation: ABL1
Target Synonym: Abelson tyrosine protein kinase 1,ABL 1,bcr/abl,JTK7,p150,Proto-oncogene c-Abl,v abl
Background: Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
- Molecular Weight
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Calculated MW: 28.93 kDa
Observed MW: 35 kDa
- UniProt
- A0A2K5X6F2
- Pathways
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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