FLT4 Protein (AA 25-775) (Fc Tag)
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- Target See all FLT4 Proteins
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-775
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FLT4 protein is labelled with Fc Tag.
- Purpose
- Mouse VEGF R3/FLT4 Protein
- Sequence
- Tyr25-Glu775
- Characteristics
- Recombinant Mouse VEGF R3/FLT4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr25-Glu775.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product FLT4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
- Alternative Name
- VEGF R3 (FLT4 Products)
- Synonyms
- FLT41 Protein, LMPH1A Protein, PCL Protein, VEGFR3 Protein, AI323512 Protein, Chy Protein, Flt-4 Protein, VEGFR-3 Protein, Vegfr3 Protein, cb1059 Protein, fms related tyrosine kinase 4 Protein, FMS-like tyrosine kinase 4 Protein, fms-related tyrosine kinase 4 Protein, FLT4 Protein, Flt4 Protein, flt4 Protein
- Background
- Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.
- Molecular Weight
- 111.69 kDa. Due to glycosylation, the protein migrates to 115-160 kDa based on Tris-Bis PAGE result.
- UniProt
- P35917
- Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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