PDGFRA Protein (AA 29-528) (His tag)
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- Target See all PDGFRA Proteins
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-528
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDGFRA protein is labelled with His tag.
- Purpose
- Mouse PDGF R alpha/PDGFRA Protein
- Sequence
- Ser29-Ala528
- Characteristics
- Recombinant Mouse PDGF R alpha/PDGFRA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser29-Ala528.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product PDGFRA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- Alternative Name
- PDGF R alpha (PDGFRA Products)
- Synonyms
- AI115593 Protein, CD140a Protein, Pdgfr-2 Protein, APDGFR Protein, PDGFACE Protein, CD140A Protein, PDGFR-2 Protein, PDGFR2 Protein, RHEPDGFRA Protein, PDGFR Protein, PDGFR-A Protein, platelet derived growth factor receptor alpha Protein, platelet derived growth factor receptor, alpha polypeptide Protein, platelet-derived growth factor receptor, alpha polypeptide L homeolog Protein, platelet-derived growth factor receptor, alpha polypeptide Protein, PDGFRA Protein, Pdgfra Protein, pdgfra.L Protein
- Background
- Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF.
- Molecular Weight
- 57.08 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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