PAI1 Protein (AA 24-402) (His tag)
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- Target See all PAI1 (SERPINE1) Proteins
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-402
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PAI1 protein is labelled with His tag.
- Purpose
- Rat PAI-1 Protein
- Sequence
- Ser24-Pro402
- Characteristics
- Recombinant Rat PAI-1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser24-Pro402.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product SERPINE1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in 50 mM HEPES, 300 mM NaCl, 1 mM TCEP ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Alternative Name
- PAI-1 (SERPINE1 Products)
- Synonyms
- PAI Protein, PAI-1 Protein, PAI1 Protein, PLANH1 Protein, SERPINE1 Protein, si:ch211-138a11.1 Protein, Planh1 Protein, PAI1A Protein, Pai1 Protein, Pai1aa Protein, Planh Protein, RATPAI1A Protein, serpin family E member 1 Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog Protein, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 Protein, serine (or cysteine) peptidase inhibitor, clade E, member 1 Protein, SERPINE1 Protein, serpine1.L Protein, serpine1 Protein, Serpine1 Protein
- Background
- PAI-1 (plasminogen activator inhibitor-1) is a member of plasminogen cascade with an inhibitory role in plasmin activation. PAI-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resistant states.
- Molecular Weight
- 43.73 kDa. Due to glycosylation, the protein migrates to 48-60 kDa based on Tris-Bis PAGE result.
- UniProt
- P20961
- Pathways
- p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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