Oncostatin M Receptor Protein (OSMR) (AA 28-735) (His tag)
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- Target See all Oncostatin M Receptor (OSMR) Proteins
- Oncostatin M Receptor (OSMR)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-735
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Origin
- Dog
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Oncostatin M Receptor protein is labelled with His tag.
- Purpose
- Canine OSMR Protein
- Sequence
- Glu28-Pro735
- Characteristics
- Recombinant Canine OSMR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Pro735.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product OSMR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Oncostatin M Receptor (OSMR)
- Alternative Name
- OSMR (OSMR Products)
- Synonyms
- OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein
- Background
- OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
- Molecular Weight
- 81.73 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A8I3MI11
- Pathways
- JAK-STAT Signaling, Growth Factor Binding
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