OGN Protein (AA 21-298) (His tag)
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- Target See all OGN Proteins
- OGN (Osteoglycin (OGN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-298
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This OGN protein is labelled with His tag.
- Purpose
- Human OGN/Osteoglycin Protein
- Sequence
- Pro21-Phe298
- Characteristics
- Recombinant Human OGN/Osteoglycin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Pro21-Phe298.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product OGN Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- OGN (Osteoglycin (OGN))
- Alternative Name
- OGN (OGN Products)
- Synonyms
- OG Protein, OIF Protein, SLRR3A Protein, MGC53032 Protein, zgc:113545 Protein, si:ch211-103f16.4 Protein, 3110079A16Rik Protein, mimecan Protein, mimican Protein, osteoglycin Protein, osteoglycin L homeolog Protein, OGN Protein, ogn.L Protein, ogn Protein, Ogn Protein
- Background
- Osteoglycin (OGN, a.k.a. mimecan) belongs to cluster III of the small leucine-rich proteoglycans (SLRP) of the extracellular matrix (ECM). In vertebrates OGN is a characteristic ECM protein of bone. The function of OGN has mainly been studied in mammals in which it regulates collagen fibrillogenesis, the efficiency of which is increased when it is processed by BMP-1/Tolloid-like metalloproteinases. OGN has a role in wound healing in the cornea, in ath erosclerotic lesions and modulates myocardial integrity and remodelling. In addition, OGN enhances the neurite outgrowth promoted by insulin-like growth factor-2 and IGF binding protein-2.
- Molecular Weight
- 32.83 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
- UniProt
- P20774
- Pathways
- Glycosaminoglycan Metabolic Process
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