LY6G6D Protein (AA 20-104) (Biotin)
LY6G6D
Origin: Human
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
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- Target See all LY6G6D Proteins
- LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-104
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LY6G6D protein is labelled with Biotin.
- Purpose
- Biotinylated Human LY6G6D Protein
- Sequence
- Asn20-Ser104
- Characteristics
- Recombinant Biotinylated Human LY6G6D Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Asn20-Ser104.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product LY6G6D Protein
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Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D) (AA 20-104) protein (His tag)
LY6G6D Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D) (AA 20-104) protein (His tag)LY6G6D Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))
- Alternative Name
- LY6G6D (LY6G6D Products)
- Synonyms
- C6orf23 Protein, G6D Protein, LY6-D Protein, MEGT1 Protein, NG25 Protein, A930024F17Rik Protein, G6d Protein, G6f Protein, NG32 Protein, Ly6-D Protein, Ng25 Protein, lymphocyte antigen 6 family member G6D Protein, lymphocyte antigen 6 complex, locus G6D Protein, LY6G6D Protein, Ly6g6d Protein
- Background
- LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
- Molecular Weight
- 12.79 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Tris-Bis PAGE result.
- UniProt
- O95868
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