IgG Protein (AA 101-323)
Origin: Rabbit
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Target See all IgG Proteins
- IgG
- Protein Type
- Recombinant
- Protein Characteristics
- AA 101-323
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Origin
- Rabbit
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Source
- HEK-293 Cells
- Purpose
- Rabbit IgG Protein
- Sequence
- Ser101-Lys323 (T185A, N284S)
- Characteristics
- Recombinant Rabbit IgG Protein is expressed from HEK293 without tag.It contains Ser101-Lys323 (T185A, N284S).
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22 μm filtered solution in PBS, 150 mM Nacl, 10 % Glycerol ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IgG
- Abstract
- IgG Products
- Target Type
- Antibody
- Background
- Immunoglobulin G (IgG) glycosylation can modulate antibody effector functions. Depending on the precise composition of the sugar moiety attached to individual IgG glycovariants either pro- or anti-inflammatory effector pathways can be initiated via differential binding to type I or type II Fc-receptors. Rabbits make high-affinity IgG antibodies, all of which bind with high affinity to Protein A from Staphylococcus aureus and Protein G from Group G Streptococcus.
- Molecular Weight
- 25.13 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.
- UniProt
- P01870
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