HIST3H2A Protein (AA 2-130)
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- Target See all HIST3H2A Proteins
- HIST3H2A (Histone H2A Type 3 (HIST3H2A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-130
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Human Histone H2A type 3 Protein
- Sequence
- Ser2-Lys130
- Characteristics
- Recombinant Human Histone H2A type 3 Protein is expressed from E.coli without tag.It contains Ser2-Lys130.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HIST3H2A (Histone H2A Type 3 (HIST3H2A))
- Alternative Name
- Histone H2A type 3 (HIST3H2A Products)
- Synonyms
- H2a Protein, histone cluster 3, H2a Protein, histone cluster 3 H2A Protein, Hist3h2a Protein, HIST3H2A Protein
- Background
- The family of histone H2A proved that there are a lot of variants associated with cancer development. HIST3H2A is a promising biomarker for predicting prognosis of pancreatic cancer, and it could be a potential therapeutic target. HIST3H2A might regulate the progression of tumor immune in pancreatic cancer through modulating the JAK-STAT pathway. In addition, the role HIST3H2A in pancreatic cancer may be related to DCST1-AS1, HIST1H2B, SLC12A9-AS1.
- Molecular Weight
- 13.99 kDa. The protein migrates to 15-20 kDa based on Tris-Bis PAGE result.
- UniProt
- Q7L7L0
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