FDPS Protein (AA 1-353) (His tag)
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- Target See all FDPS Proteins
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-353
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FDPS protein is labelled with His tag.
- Purpose
- Human FDPS Protein
- Sequence
- Met1-Lys353
- Characteristics
- Recombinant Human FDPS Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys353.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product FDPS Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
- Alternative Name
- FDPS (FDPS Products)
- Synonyms
- CG12389 Protein, DmFPPS Protein, DmFPPSase Protein, DmFPS Protein, Dmel\\CG12389 Protein, FPS Protein, fpps Protein, fps Protein, l(2)k06103 Protein, v(2)k03514 Protein, NCU01175.1 Protein, 16.m00760 Protein, DDBDRAFT_0206220 Protein, DDBDRAFT_0215017 Protein, DDB_0206220 Protein, DDB_0215017 Protein, FPPS Protein, Ac2-125 Protein, (2E Protein, 6030492I17Rik Protein, AI256750 Protein, Fdpsl1 Protein, mKIAA1293 Protein, Farnesyl pyrophosphate synthase Protein, farnesyl diphosphate synthase Protein, farnesyl diphosphate synthase L homeolog Protein, farnesyl pyrophosphate synthase Protein, farnesyl pyrophosphate synthetase Protein, farnesyl-pyrophosphate synthetase Protein, FDP synthase Protein, Farnesyl pyrophosphate synthetase Protein, farnesyl diphosphate synthetase Protein, farnesyl pyrophosphate synthase 1 Protein, Fpps Protein, fdps Protein, fdps.L Protein, MGG_08649 Protein, TP03_0857 Protein, Tb09.160.4300 Protein, fpp Protein, BBOV_I000120 Protein, fps Protein, fpps Protein, FDPS Protein, Fdps Protein, fps1 Protein
- Background
- Farnesyl pyrophosphate synthase (FPPS, also known as farnesyl diphosphate synthase (FDPS)) is one of the key enzymes involved in the mevalonate pathway and as such is widely expressed. FPPS modulators, specifically FPPS inhibitors, are useful in treating a number of diseases, including bone-related disorders characterized by excessive bone resorption, for example, osteoporosis, cancer metathesis to bone and infectious diseases caused by certain parasites.
- Molecular Weight
- 41.93 kDa same as Tris-Bis PAGE result.
- NCBI Accession
- NP_001129294
- Pathways
- Regulation of Muscle Cell Differentiation
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