Claudin 4 Protein-VLP (CLDN4) (AA 1-209)
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- Target See all Claudin 4 (CLDN4) Proteins
- Claudin 4 (CLDN4)
- Protein Type
- VLP
- Protein Characteristics
- AA 1-209
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human Claudin 4 Protein-VLP
- Sequence
- Met1-Val209
- Characteristics
- Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
- Purity
- > 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CLDN4 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
Notice: If you need it for immunization, Do Not use any adjuvant. - Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Claudin 4 (CLDN4)
- Alternative Name
- Claudin 4 (CLDN4 Products)
- Synonyms
- CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
- Background
- Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
- Molecular Weight
- 23.31 kDa.
- UniProt
- O14493
- Pathways
- Hepatitis C
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