CD300a Protein (CD300A) (AA 18-178) (Biotin)

Catalog No. ABIN7504259

Product Details

Target: CD300a (CD300A)

Protein Type: Recombinant

Protein Characteristics: AA 18-178

Origin: Cynomolgus

Source: HEK-293 Cells

Purification tag / Conjugate: This CD300a protein is labelled with Biotin.

Purpose: Biotinylated Cynomolgus CD300A Protein

Sequence: Leu18-Gln178

Characteristics: Recombinant Biotinylated Cynomolgus CD300A Protein is expressed from HEK293 with Avi tag at the C-Terminus.It contains Leu18-Gln178.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CD300a (CD300A)

Alternative Name: CD300A (CD300A Products)

Synonyms: CD300L-B1 Protein, CD300A Protein, clm8 Protein, B230315M08Rik Protein, Clm8 Protein, LMIR1 Protein, MAIR-I Protein, MAIR-Ia Protein, MMAC8 Protein, Pigr4 Protein, mcpir1 Protein, CLM-8 Protein, CMRF-35-H9 Protein, CMRF-35H Protein, CMRF35-H Protein, CMRF35-H9 Protein, CMRF35H Protein, CMRF35H9 Protein, IGSF12 Protein, IRC1 Protein, IRC1/IRC2 Protein, IRC2 Protein, IRp60 Protein, CD300 molecule like family member g Protein, CD300a molecule Protein, CMRF35-like molecule 8 Protein, CD300A molecule Protein, Cd300a molecule Protein, CD300LG Protein, CD300A Protein, LOC483289 Protein, clm8 Protein, Cd300a Protein

Background: CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI), however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation.

Molecular Weight: 19.44 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

UniProt: A0A7N9CE79

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process