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NKG2A & CD94 protein (mFc Tag)

MALS verified Origin: Rat Host: HEK-293 Cells Recombinant 95 %
Catalog No. ABIN7488870
  • Target
    NKG2A & CD94
    Protein Type
    Recombinant
    Origin
    • 8
    • 3
    • 3
    Rat
    Source
    • 14
    HEK-293 Cells
    Purification tag / Conjugate
    mFc Tag
    Purpose
    Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)
    Sequence
    Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94)
    Characteristics
    Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94) (Accession # O54872-1(NKG2A) & O35778-1(CD94).
    Purity
    95 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
  • Comment

    This protein carries a mouse IgG2a Fc tag at the C-terminus. (mFc(mIgG2a) The protein has a calculated MW of 61.0 kDa. The protein migrates as 67-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    NKG2A & CD94
    Alternative Name
    NKG2A&CD94
    Background
    CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
    Molecular Weight
    61.0 kDa
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