NKG2A & CD94 protein (mFc Tag)
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- Target
- NKG2A & CD94
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- mFc Tag
- Purpose
- Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)
- Sequence
- Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94)
- Characteristics
- Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94) (Accession # O54872-1(NKG2A) & O35778-1(CD94).
- Purity
- 95 %
- Endotoxin Level
- 1.0 EU per μg
- Grade
- MALS verified
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- Comment
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This protein carries a mouse IgG2a Fc tag at the C-terminus. (mFc(mIgG2a) The protein has a calculated MW of 61.0 kDa. The protein migrates as 67-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- NKG2A & CD94
- Alternative Name
- NKG2A&CD94
- Background
- CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
- Molecular Weight
- 61.0 kDa
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