SLC1A2 Protein (DYKDDDDK Tag,His tag)

Catalog No. ABIN7489012

Product Details

Target: SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SLC1A2 protein is labelled with DYKDDDDK Tag,His tag.

Purpose: Human SLC1A2 Protein, Flag,His Tag (Detergent)

Sequence: Ala 2 - Lys 574

Characteristics: Human SLC1A2 Protein, Flag,His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Lys 574 (Accession # P43004).

Purity: 90 %

Endotoxin Level: 1.0 EU per μg

Application Details

Comment:

This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. (Flag , 10xHis) The protein has a calculated MW of 66.0 kDa. The protein migrates as 55-116 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5

Storage: -80 °C

Storage Comment: -70°C

Target Details

Target: SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Alternative Name: SLC1A2 (SLC1A2 Products)

Synonyms: CG3159 Protein, Dmel\\CG3159 Protein, EAAT Protein, dEAAT2 Protein, dEaat2 Protein, Eaat Protein, GB16377 Protein, EAAT2 Protein, SLC1A2 Protein, Eaat2 Protein, Glt Protein, Glt-1 Protein, GLT-1 Protein, 1700091C19Rik Protein, 2900019G14Rik Protein, AI159670 Protein, GLT1 Protein, MGLT1 Protein, eaat2 Protein, fj34b12 Protein, slc1a2 Protein, wu:fj34b12 Protein, zgc:65897 Protein, Excitatory amino acid transporter 2 Protein, excitatory amino acid transporter 2 Protein, solute carrier family 1 member 2 Protein, solute carrier family 1 (glial high affinity glutamate transporter), member 2 Protein, solute carrier family 1 (glial high affinity glutamate transporter), member 2b Protein, Eaat2 Protein, Eaat-2 Protein, SLC1A2 Protein, VDBG_06180 Protein, EUBELI_01747 Protein, Trebr_0139 Protein, Slc1a2 Protein, slc1a2b Protein

Background: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

Molecular Weight: 66.0 kDa

Pathways: Dicarboxylic Acid Transport