Glucagon Receptor Protein-VLP (GCGR)
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- Target See all Glucagon Receptor (GCGR) Proteins
- Glucagon Receptor (GCGR)
- Protein Type
- VLP
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human GCGR / Glucagon receptor Full Length Protein (VLP)
- Sequence
- Ala 26 - Asn 432
- Characteristics
- Human GCGR Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Asn 432 (Accession # P47871-1).
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product GCGR Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, Arginine, pH 7.4
- Storage
- -80 °C
- Storage Comment
- -70°C
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- Target
- Glucagon Receptor (GCGR)
- Alternative Name
- GCGR (GCGR Products)
- Synonyms
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- Background
- The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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