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Glucagon Receptor Protein-VLP (GCGR)

GCGR Origin: Human Host: HEK-293 Cells VLP
Catalog No. ABIN7489074
  • Target See all Glucagon Receptor (GCGR) Proteins
    Glucagon Receptor (GCGR)
    Protein Type
    VLP
    Origin
    • 4
    • 1
    Human
    Source
    • 5
    HEK-293 Cells
    Purpose
    Human GCGR / Glucagon receptor Full Length Protein (VLP)
    Sequence
    Ala 26 - Asn 432
    Characteristics
    Human GCGR Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Asn 432 (Accession # P47871-1).
    Endotoxin Level
    1.0 EU per μg
    Top Product
    Discover our top product GCGR Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, Arginine, pH 7.4
    Storage
    -80 °C
    Storage Comment
    -70°C
  • Target
    Glucagon Receptor (GCGR)
    Alternative Name
    GCGR (GCGR Products)
    Synonyms
    GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
    Background
    The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of  type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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