GAS6 Protein (AA 471-678) (His tag)
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- Target See all GAS6 Proteins
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 471-678
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GAS6 protein is labelled with His tag.
- Purpose
- Human GAS6 (471-678) Protein, His Tag (MALS verified)
- Sequence
- Phe 471 - Ala 678
- Characteristics
- Human GAS6 (471-678) Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Phe 471 - Ala 678 (Accession # Q14393-2).
- Purity
- 90 %
- Endotoxin Level
- 1.0 EU per μg
- Grade
- MALS verified
- Top Product
- Discover our top product GAS6 Protein
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- Comment
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This protein carries a polyhistidine tag at the N-terminus. (10xHis) The protein has a calculated MW of 24.5 kDa. The protein migrates as 26-27 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Alternative Name
- GAS6 (GAS6 Products)
- Synonyms
- fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein
- Background
- GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
- Molecular Weight
- 24.5 kDa
- Pathways
- RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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