Claudin 4 Protein (CLDN4) (His tag,Twin-Strep tag)
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- Target See all Claudin 4 (CLDN4) Proteins
- Claudin 4 (CLDN4)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Insect Cells
- Purification tag / Conjugate
- This Claudin 4 protein is labelled with His tag,Twin-Strep tag.
- Purpose
- Human Claudin-4 Protein, His,Twin-Strep Tag (Detergent)
- Sequence
- Met 1 - Val 209
- Characteristics
- Human Claudin-4 Protein, His,Twin-Strep Tag is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Val 209 (Accession # O14493-1).
- Purity
- 90 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product CLDN4 Protein
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- Comment
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This protein carries a polyhistidine tag at the N-terminus and a twin strep tag at the C-terminus. (10xHis , Twin-Strep) The protein has a calculated MW of 27.5 kDa. The protein migrates as 23-24 kDa under reducing (R) condition (SDS-PAGE).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 50 mM Tris, 150 mM NaCl, DDM, CHS, pH 7.5
- Storage
- -80 °C
- Storage Comment
- -70°C
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- Target
- Claudin 4 (CLDN4)
- Alternative Name
- Claudin-4 (CLDN4 Products)
- Synonyms
- CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
- Background
- The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
- Molecular Weight
- 27.5 kDa
- Pathways
- Hepatitis C
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