CDH6 Protein (Biotin,His-Avi Tag)

Catalog No. ABIN7482345

Product Details

Target: CDH6 (K-Cadherin (CDH6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CDH6 protein is labelled with Biotin,His-Avi Tag.

Purpose: Biotinylated Human Cadherin-6 / KCAD / CDH6 Protein, His,Avitag™ (MALS verified)

Sequence: Thr 19 - Ala 615

Characteristics: Biotinylated Human Cadherin-6 Protein, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P55285-1).

Purity: 85 %

Endotoxin Level: 1.0 EU per μg

Grade: MALS verified

Application Details

Comment:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 70.0 kDa. The protein migrates as 53 kDa, 65 kDa and 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: Cadherin-6 (CDH6 Products)

Synonyms: KCAD Protein, K-cadherin Protein, cad6 Protein, cadherin-6 Protein, CAD6 Protein, c-cad6B Protein, cadherin 6 Protein, Cdh6 Protein, CDH6 Protein

Background: Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Molecular Weight: 70.0 kDa

Pathways: Cell-Cell Junction Organization