NGFB Protein

Catalog No. ABIN7489071

Product Details

Target: NGFB (Nerve Growth Factor beta (NGFB))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purpose: ActiveMax® Mouse Beta-NGF Protein, Tag Free (MALS verified)

Sequence: Ser 122 - Gly 241

Characteristics: ActiveMax® Mouse Beta-NGF Protein, Tag Free is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Gly 241 (Accession # P01139).

Purity: 95 %

Endotoxin Level: 0.1 EU per μg

Grade: MALS verified

Application Details

Comment:

This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as <14 kDa under reducing (R) condition (SDS-PAGE).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 20 mM NaAC, 150 mM NaCl, pH 5.5

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: Beta-NGF (NGFB Products)

Synonyms: NGFB Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, hsan5 Protein, beta-ngf Protein, Ngfb Protein, Beta-NGF Protein, HSAN5 Protein, beta-NGF Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, beta-Nerve growth factor Protein, nerve growth factor (beta polypeptide) Protein, NGF Protein, ngfb Protein, FPV072 Protein, FPV076 Protein, ngf Protein, Ngf Protein

Background: Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.

Molecular Weight: 13.5 kDa

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size