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- Target See all UTS2R products
- UTS2R (Urotensin 2 Receptor (UTS2R))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human UTS2R full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- UTS2R (Urotensin 2 Receptor (UTS2R))
- Alternative Name
- UTS2R (UTS2R Products)
- Synonyms
- MGC84372 Protein, GPR14 Protein, UR-2-R Protein, UTR Protein, UTR2 Protein, Gpr14 Protein, Senr Protein, SENR Protein, urotensin 2 receptor Protein, urotensin 2 receptor L homeolog Protein, UTS2R Protein, uts2r.L Protein, Uts2r Protein
- Background
- High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- The human full length UTS2R protein has a MW of 41.9 kDa
- UniProt
- Q9UKP6
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