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- Target See all GPR64 Proteins
- GPR64 (G Protein-Coupled Receptor 64 (GPR64))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human ADGRG2 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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G Protein-Coupled Receptor 64 (GPR64) (AA 38-627) protein (His tag)
GPR64 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR64 (G Protein-Coupled Receptor 64 (GPR64))
- Alternative Name
- ADGRG2 (GPR64 Products)
- Synonyms
- EDDM6 Protein, HE6 Protein, TM7LN2 Protein, AW212196 Protein, B830041D06Rik Protein, Me6 Protein, He6 Protein, Re6 Protein, adhesion G protein-coupled receptor G2 Protein, ADGRG2 Protein, Adgrg2 Protein
- Background
- A member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family.
- Molecular Weight
- The human full length ADGRG2 protein has a MW of 111.6 kDa
- UniProt
- Q8IZP9
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