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- Target See all TMEM180 products
- TMEM180 (Transmembrane Protein 180 (TMEM180))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human MFSD13A full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- TMEM180 (Transmembrane Protein 180 (TMEM180))
- Alternative Name
- MFSD13A (TMEM180 Products)
- Synonyms
- C10orf77 Protein, bA18I14.8 Protein, 4930449A08Rik Protein, 4930538D17Rik Protein, major facilitator superfamily domain containing 13A Protein, major facilitator superfamily domain containing 13a Protein, MFSD13A Protein, Mfsd13a Protein
- Background
- MFSD13A, also called Transmembrane protein 180 (TMEM180), is a transmembrane protein that belongs to the glycoside-pentoside-hexuronide (GPH):cation symporter family. Members of this family catalyze symport of a sugar molecule with a monovalent cation (H or Na ). MFSD13A is classified as a member of the cation symporter family and a multi-pass membrane protein, but little information is available regarding its substrate and topology.
- Molecular Weight
- The human full length MFSD13A protein has a MW of 57.4 kDa
- UniProt
- Q14CX5
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