SLC4A7 Protein
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- Target See all SLC4A7 Proteins
- SLC4A7 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 7 (SLC4A7))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human SLC4A7 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product SLC4A7 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- SLC4A7 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 7 (SLC4A7))
- Alternative Name
- SLC4A7 (SLC4A7 Products)
- Synonyms
- nbc2 Protein, nbc3 Protein, sbc2 Protein, nbcn1 Protein, slc4a6 Protein, MGC83246 Protein, SLC4A7 Protein, NBC2 Protein, NBC3 Protein, NBCN1 Protein, SBC2 Protein, SLC4A6 Protein, E430014N10Rik Protein, NBCn1 Protein, NBCn1-G Protein, solute carrier family 4 member 7 Protein, solute carrier family 4, sodium bicarbonate cotransporter, member 7 L homeolog Protein, solute carrier family 4, sodium bicarbonate cotransporter, member 7 Protein, SLC4A7 Protein, slc4a7.L Protein, slc4a7 Protein, Slc4a7 Protein
- Background
- This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
- Molecular Weight
- The human full length SLC4A7 protein has a MW of 136.5 kDa
- UniProt
- Q9Y6M7
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