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LGR6 Protein

LGR6 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
Catalog No. ABIN7491691
  • Target See all LGR6 Proteins
    LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
    Protein Type
    Synthetic Nanodisc
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    HEK-293 Cells
    Purpose
    Human LGR6 full length protein-synthetic nanodisc
    Characteristics
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • Comment

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
    Alternative Name
    LGR6 (LGR6 Products)
    Synonyms
    LGR6 Protein, GPCR Protein, VTS20631 Protein, A530037C04Rik Protein, D830026M09 Protein, RGD1560339 Protein, leucine rich repeat containing G protein-coupled receptor 6 Protein, leucine-rich repeat-containing G protein-coupled receptor 6 Protein, LGR6 Protein, Lgr6 Protein
    Background
    The protein is a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding.
    Molecular Weight
    The human full length LGR6 protein has a MW of 104.3 kDa
    UniProt
    Q9HBX8
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