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- Target See all CXCR5 Proteins
- CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))
- Protein Type
- Synthetic Nanodisc
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CXCR5 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Chemokine (C-X-C Motif) Receptor 5 (CXCR5) (AA 1-53) protein (Fc Tag)
CXCR5 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Receptor 5 (CXCR5) (AA 1-372) protein (GST tag)CXCR5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))
- Alternative Name
- CXCR5 (CXCR5 Products)
- Synonyms
- BLR1 Protein, CRL1 Protein, CD185 Protein, MDR15 Protein, Blr1 Protein, CXC-R5 Protein, CXCR-5 Protein, Gpcr6 Protein, NLR Protein, C-X-C motif chemokine receptor 5 Protein, chemokine (C-X-C motif) receptor 5 Protein, CXCR5 Protein, Cxcr5 Protein
- Background
- A multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches.
- Molecular Weight
- The human full length CXCR5 protein has a MW of 42.0 kDa
- UniProt
- P32302
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