SLC1A5 Protein

Catalog No. ABIN7491727

Product Details

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Protein Type: Synthetic Nanodisc

Origin: Human

Source: HEK-293 Cells

Purpose: Human SLC1A5 full length protein-synthetic nanodisc

Characteristics: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Application Details

Comment:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Alternative Name: SLC1A5 (SLC1A5 Products)

Synonyms: aaat Protein, asct2 Protein, atbo Protein, m7v1 Protein, m7vs1 Protein, r16 Protein, rdrc Protein, AAAT Protein, ASCT2 Protein, ATBO Protein, M7V1 Protein, M7VS1 Protein, R16 Protein, RDRC Protein, Slc1a7 Protein, Asct2 Protein, H4-ASCT2 Protein, solute carrier family 1 (neutral amino acid transporter), member 5 Protein, solute carrier family 1 member 5 S homeolog Protein, solute carrier family 1 member 5 Protein, slc1a5 Protein, slc1a5.S Protein, SLC1A5 Protein, Slc1a5 Protein

Background: The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011]

Molecular Weight: The human full length SLC1A5 protein has a MW of 56.4 kDa

UniProt: Q15758

Pathways: Dicarboxylic Acid Transport, Warburg Effect