ENTPD2 Protein

Catalog No. ABIN7491633

Product Details

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Protein Type: Synthetic Nanodisc

Origin: Human

Source: HEK-293 Cells

Purpose: Human ENTPD2 full length protein-synthetic nanodisc

Characteristics: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Application Details

Comment:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))

Alternative Name: ENTPD2 (ENTPD2 Products)

Synonyms: MGC76207 Protein, MGC151796 Protein, CD39L1 Protein, NTPDase-2 Protein, Cd39l1 Protein, NTPDase2 Protein, ectonucleoside triphosphate diphosphohydrolase 2 Protein, Ectonucleoside triphosphate diphosphohydrolase 2 Protein, entpd2 Protein, ENTPD2 Protein, enp2 Protein, Entpd2 Protein

Background: The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Molecular Weight: The human full length ENTPD2 protein has a MW of 53.7 kDa

UniProt: Q9Y5L3