SLC25A4 Protein
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- Target See all SLC25A4 Proteins
- SLC25A4 (Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 4 (SLC25A4))
- Protein Type
- Synthetic Nanodisc
- Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human SLC25A4 full length protein-synthetic nanodisc
- Characteristics
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product SLC25A4 Protein
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- Comment
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- SLC25A4 (Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 4 (SLC25A4))
- Alternative Name
- SLC25A4 (SLC25A4 Products)
- Synonyms
- 1 Protein, AAC1 Protein, ANT Protein, ANT 1 Protein, ANT1 Protein, PEO2 Protein, PEO3 Protein, T1 Protein, AU019225 Protein, Ant1 Protein, ant Protein, ant1 Protein, peo2 Protein, peo3 Protein, MANT1 Protein, SLC25A5 Protein, fa22e07 Protein, wu:fa22e07 Protein, zgc:77591 Protein, slc25a4 Protein, solute carrier family 25 member 4 Protein, solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 Protein, adenine nucleotide translocator Protein, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 Protein, solute carrier family 25 member 4 L homeolog Protein, SLC25A4 Protein, Slc25a4 Protein, slc25a4 Protein, ANT1 Protein, slc25a4.L Protein
- Background
- The protein functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
- Molecular Weight
- The human full length SLC25A4 protein has a MW of 33.1 kDa
- UniProt
- P12235
- Pathways
- Proton Transport, Dicarboxylic Acid Transport
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