Osteoactivin Protein (GPNMB) (AA 23-496) (His tag)
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- Target See all Osteoactivin (GPNMB) Proteins
- Osteoactivin (GPNMB)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-496
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Osteoactivin protein is labelled with His tag.
- Purpose
- Recombinant Human GPNMB Protein with C-terminal 6xHis tag
- Specificity
- GPNMB (Lys23-Met496) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product GPNMB Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Osteoactivin (GPNMB)
- Alternative Name
- GPNMB (GPNMB Products)
- Synonyms
- HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein
- Background
- The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 53.9 kDa after removal of the signal peptide. The apparent molecular mass of GPNMB-His is 70-130 kDa due to glycosylation.
- UniProt
- Q14956
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