CD14 Protein (CD14) (AA 20-352) (His tag)
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- Target See all CD14 Proteins
- CD14
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-352
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD14 protein is labelled with His tag.
- Purpose
- Recombinant Human CD14(20-352) Protein with C-terminal 7xHis tag
- Specificity
- CD14 (Thr20-Cys352) 7xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD14 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD14
- Alternative Name
- CD14 (CD14 Products)
- Synonyms
- CD14 molecule Protein, CD14 antigen Protein, CD14 Protein, Cd14 Protein
- Background
- The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
- Molecular Weight
- predicted molecular mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of CD14(20-352)-7xHis is 35-55 kDa due to glycosylation.
- UniProt
- P08571
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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