SIGLEC5 Protein (AA 17-434) (His tag)
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- Target See all SIGLEC5 Proteins
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-434
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIGLEC5 protein is labelled with His tag.
- Purpose
- Recombinant Human SIGLEC5 Protein with C-terminal 6xHis tag
- Specificity
- SIGLEC5 (Glu17-Thr434) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SIGLEC5 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
- Alternative Name
- SIGLEC5 (SIGLEC5 Products)
- Synonyms
- CD170 Protein, CD33L2 Protein, OB-BP2 Protein, OBBP2 Protein, SIGLEC-5 Protein, sialic acid binding Ig like lectin 5 Protein, sialic acid-binding Ig-like lectin 5 Protein, sialic acid binding Ig-like lectin 5 Protein, SIGLEC5 Protein, LOC100597560 Protein, Siglec5 Protein
- Background
- This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
- Molecular Weight
- predicted molecular mass of 47.2 kDa after removal of the signal peptide. The apparent molecular mass of SIGLEC5-His is 55-100 kDa due to glycosylation.
- UniProt
- O15389
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