C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 55-229) protein (His tag)
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- Target See all C-Type Lectin Domain Family 1, Member B (CLEC1B) Proteins
- C-Type Lectin Domain Family 1, Member B (CLEC1B)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 55-229
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Recombinant Human CLEC1B Protein with N-terminal 6xHis tag
- Specificity
- 6xHis tag CLEC1B (Ser55-Pro229)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- C-Type Lectin Domain Family 1, Member B (CLEC1B)
- Alternative Name
- CLEC1B (CLEC1B Products)
- Synonyms
- 1810061I13Rik Protein, CLEC2 Protein, CLEC2B Protein, PRO1384 Protein, QDED721 Protein, Clec-2 Protein, Clec2 Protein, CLEC1B Protein, RGD1563517 Protein, CLEC9A Protein, C-type lectin domain family 1 member B Protein, C-type lectin domain family 1, member b Protein, C-type lectin domain family 1, member B Protein, CLEC1B Protein, Clec1b Protein
- Target Type
- Viral Protein
- Background
- Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1, MIM 602894) and NKG2D (KLRC4, MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
- Molecular Weight
- predicted molecular mass of 21.5 kDa after removal of the signal peptide. The apparent molecular mass of His-CLEC1B is 25-35 kDa due to glycosylation.
- UniProt
- Q9P126
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