Claudin 4 Protein (CLDN4) (AA 145-157) (Fc Tag)
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- Target See all Claudin 4 (CLDN4) Proteins
- Claudin 4 (CLDN4)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 145-157
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Claudin 4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CLDN4(145-157) Protein with C-terminal human Fc tag
- Specificity
- CLDN4 (Gln145-Lys157) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CLDN4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Claudin 4 (CLDN4)
- Alternative Name
- CLDN4 (CLDN4 Products)
- Synonyms
- CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
- Background
- The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
- Molecular Weight
- predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of CLDN4(145-157)-hFc is 25-35 kDa due to glycosylation.
- UniProt
- O14493
- Pathways
- Hepatitis C
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